The VS20WAVE-DGGE is a complete system for DNA mutation analysis. Utilizing the innovative vertical screw-clamp technology of the VS20-WAVE system, the VS20WAVE-DGGE is fully equipped with a temperature control unit, mixer, gradient mixer, and casting accessories to perform specific mutation analysis applications.

The powerful microprocessor-controlled PID temperature control unit allows for the execution of various mutation detection techniques between ambient temperature and 70°C, while the simple four-screw design of the WAVE array speeds up the setup of denaturing PAGE gels. The VS20-DGGE can be used to scan single base pair changes in the following applications:

• Parallel Denaturing Gradient Gel Electrophoresis (DGGE)

• Constant Denaturing Gradient Gel Electrophoresis (CDGE)

With a maximum throughput of 96 samples, it alleviates many of the bottlenecks associated with scanning DNA mutations by enabling the detection of numerous mutations within a few hours. The GM100 gradient mixer is provided as standard to efficiently create gradients by mixing and delivering high and low-density denaturant solutions. The PP1 peristaltic pump is also recommended for the linear and repeatable delivery of gradient gels.

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